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  • Mouse Anti-Human IL-15 mAb, Biotinylated

Mouse Anti-Human IL-15 mAb, Biotinylated

Synonyms:

Interleukin-15

Species:

Human

Cat. No.:

CMH200 pdf (datasheet)

Quantity/Size:

50 μg

Price:

$480.00 BUY

Description:

IL-15 is produced largely by dendritic cells, monocytes, and stromal cells. The IL-15R complex consists of three chains, IL-15R , IL-2/15R beta, and C chains. IL-15 binds the endogenous IL-15R chain expressed by IL-15-producing cells and is trans-presented to the complex of IL-2/15R beta and C chains with the signaling capacity expressed on T cells. The recognition of IL-15 by the latter receptor chains leads to the activation of various signaling pathways including JAK1 and 3/STAT5 as well as PI3K/AKT. IL-15 has diverse functions that include promoting cytotoxicity and maintenance of memory CD8+ T cells as well as proliferation and differentiation of NK and NK T cells.

Entrez Symbol:

IL15

Uniprot Name:

Interleukin-15

Uniprot ID:

P40933

Data PDF:

CMH200

Specificity:

Human Interleukin-15

Host Species:

Mouse

Immunogen:

Highly purified (>98%) rhIL-15

Isotype:

IgG1

Conjugate:

Biotin

Formulation:

PBS

Application:

ELISA, WB

Application notes:

No reactivity with mouse, rat IL-15 and other unrelated proteins.

Storage/Stability:

Store at -80°C for 1 year