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Mouse Anti-Human HLA-E (Clone MEM-E/02) mAb

Synonyms:

HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E

Species:

Human

Cat. No.:

MON2077 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$880.00 BUY

Concentration:

1 mg/ml

Description:

MON 2077 reacts with denaturated heavy chain of human HLA-E. HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

Entrez Symbol:

HLA-E

Uniprot Name:

HLA class I histocompatibility antigen

Uniprot ID:

P13747

Data PDF:

MON2077

Specificity:

HLA-E

Host Species:

Mouse

Immunogen:

Recombinant human HLA-E denaturated heavy chain

Isotype:

IgG1

Clone:

MEM-E/02

Formulation:

Purified antibody in PBS with 15 mM sodium azide.

Application:

IHC-F, WB

Storage/Stability:

Store as supplied for up to 1 year at 2-8°C.