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Mouse Anti-Human CD8 (Clone MEM-31) mAb, FITC

Molecule:

CD8

Synonyms:

p32, LEU2

Species:

Human

Cat. No.:

MON1102F pdf (datasheet)

Quantity/Size:

100 tests

Price:

$920.00 BUY

Concentration:

1 mg/ml

Description:

MON1102 recognizes a conformationally-dependent epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as alpha/beta heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as alpha/alpha homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function.

Entrez Symbol:

CD8

Uniprot Name:

p32

Data PDF:

MON1102F

Specificity:

Human CD8

Host Species:

Mouse

Immunogen:

Crude thymus membrane fraction.

Isotype:

IgG2a

Clone:

MEM-31

Formulation:

Liquid. PBS, pH 7.4 containing 15 mM sodium azide

Application:

FC

Storage/Stability:

Stable for at least one year at 2-8°C.