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  • Mouse Anti-Human CD45RB (Clone MEM-55) mAb, FITC

Mouse Anti-Human CD45RB (Clone MEM-55) mAb, FITC

Synonyms:

Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, L-CA, T200, CD45

Species:

Human

Cat. No.:

MON1153F pdf (datasheet)

Quantity/Size:

100 tests

Price:

$920.00 BUY

Concentration:

1 mg/ml

Description:

MON 1153 recognizes a siliadase-sensitive epitope of CD45RB, a 180-240 kDa single chain type I membrane glycoprotein, variant of CD45 (CD45RB isoform). CD45RB is expressed on a subset of T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. Acts as a receptor for human cytomegalovirus protein UL11 and mediates binding of UL11 to T-cells, leading to reduced induction of tyrosine phosphorylation of multiple signaling proteins upon T-cell receptor stimulation and impaired T-cell proliferation.

Entrez Symbol:

PTPRC

Uniprot Name:

Receptor-type tyrosine-protein phosphatase C

Uniprot ID:

P08575-9 Isoform 7

Data PDF:

MON1153F

Specificity:

Siliadase-sensitive epitope of CD45RB

Host Species:

Mouse

Immunogen:

Human thymocytes and T lymphocytes

Isotype:

IgG1

Clone:

MEM-55

Formulation:

The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary. Storage Buffer: PBS containing BSA and 15 mM sodium

Cross Reactivity:

1381

Application:

FC

Application notes:

The antibody can be used for flow cytometry using 20 μl reagent for 100 μl of whole blood or 106 cells in a suspension.

Storage/Stability:

Store as supplied for up to 1 year at 2-8°C. Protect from light.