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  • Mouse Anti-Human CD14 (Clone MEM-18) mAb

Mouse Anti-Human CD14 (Clone MEM-18) mAb

Molecule:

CD14

Synonyms:

Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Species:

Human

Cat. No.:

MON1108 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$700.00 BUY

Concentration:

1 mg/ml

Description:

MON1108 recognizes CD14, a 55 kDa GPI-anchored glycoprotein, which is constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles.

Entrez Symbol:

CD14

Uniprot Name:

Monocyte differentiation antigen CD14

Uniprot ID:

P08571

Data PDF:

MON1108

Specificity:

Human CD14

Host Species:

Mouse

Immunogen:

A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria

Isotype:

IgG1

Clone:

MEM-18

Formulation:

Liquid. PBS, pH 7.4 containing 15 mM sodium azide

Application:

ELISA, FC, IP , WB

Storage/Stability:

Stable for at least one year at 2-8°C.