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Mouse Anti-Human CD14 (Clone MEM-15) mAb

Molecule:

CD14

Synonyms:

Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, CD14, LPS-receptor

Species:

Human

Cat. No.:

MON1072 pdf (datasheet)

Quantity/Size:

100 µg

Price:

$700.00 BUY

Concentration:

1 mg/ml

Description:

MON1072 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes; also expressed by most tissue macrophages. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.

Entrez Symbol:

CD14

Uniprot Name:

Monocyte differentiation antigen CD14

Uniprot ID:

P08571

Data PDF:

MON1072

Specificity:

Human and non-human primate CD14

Host Species:

Mouse

Immunogen:

A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria.

Isotype:

IgG1

Clone:

MEM-15

Formulation:

Liquid. PBS, pH 7.4 containing 15 mM sodium azide

Application:

FC, IP

Storage/Stability:

Stable for at least one year at 2-8°C.