• Home /
  • Mouse Anti-Human BCMA (Clone B-B54) mAb, Azide Free

Mouse Anti-Human BCMA (Clone B-B54) mAb, Azide Free

Synonyms:

Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B-cell maturation protein, BCMA, CD269

Species:

Human

Cat. No.:

CDM545A pdf (datasheet)

Quantity/Size:

200 μg

Price:

$360.00 BUY

Concentration:

1.0 mg/ml

Description:

B-cell maturation antigen (BCMA), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a receptor preferentially expressed in mature B lymphocytes, and is important for B cell development and autoimmune response. BCMA, along with two related TNFR superfamily B-cell activation factor receptor (BAFF-R) and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), critically regulate B cell proliferation and survival, as well as maturation and differentiation into plasma cells. BCMA is highly expressed on the surface of the malignant plasma cells that characterize this cancer type. BCMA is a promising novel target for antimyeloma therapies.

Entrez Symbol:

TNFRSF17

Uniprot Name:

Tumor necrosis factor receptor superfamily member 17

Uniprot ID:

Q02223

Data PDF:

CDM545

Specificity:

Recognizes both native and recombinant human BCMA

Host Species:

Mouse

Immunogen:

Recombinant human BCMA ECD with Fc Human IgG1 domain

Isotype:

IgG1 Kappa light chain

Clone:

B-B54

Formulation:

Sterile-filtered PBS, carrier and preservative free.

Application:

FC

Storage/Stability:

Store at 2-8°C.