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Mouse Anti-Human BCMA (Clone B-B54) mAb

Synonyms:

Tumor necrosis factor receptor superfamily member 17, TNFRSF17, B-cell maturation protein, BCMA, CD269

Species:

Human

Cat. No.:

CDM546 pdf (datasheet)

Quantity/Size:

200 tests

Price:

$320.00 BUY

Description:

B-cell maturation antigen (BCMA), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a receptor preferentially expressed in mature B lymphocytes, and is important for B cell development and autoimmune response. BCMA, along with two related TNFR superfamily B-cell activation factor receptor (BAFF-R) and transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI), critically regulate B cell proliferation and survival, as well as maturation and differentiation into plasma cells. BCMA is highly expressed on the surface of the malignant plasma cells that characterize this cancer type. BCMA is a promising novel target for antimyeloma therapies.

Entrez Symbol:

TNFRSF17

Uniprot Name:

Tumor necrosis factor receptor superfamily member 17

Uniprot ID:

Q02223

Data PDF:

CDM546

Specificity:

Recognizes both native and recombinant human BCMA

Host Species:

Mouse

Immunogen:

Recombinant human BCMA ECD with Fc Human IgG1 domain

Isotype:

IgG1 Kappa light chain

Clone:

B-B54

Formulation:

Sterile-filtered PBS, 1% BSA, 0.09% sodium azide

Application:

FC

Application notes:

Flow cytometry: Use 10 μl to label 10e6 cells or 100 μl of whole blood

Storage/Stability:

Store at 2-8°C.