Synonyms:
Gamma-Aminobuytric Acid Type A Receptor Rho 1 Subunit, GABA(A)Receptor, Rho 1, GABA C Receptor
Description:
GABA (gamma-aminobutyric acid) is the major inhibitory neurotransmitter in the
mammalian brain where it acts at GABA-A receptors. GABA-A receptors are
multisubunit proteins that form ligand-gated chloride channels. Chloride conductance of
these channels can be modulated by agents such as GABA, benzodiazepines and
various anesthetics that bind to the GABA-A receptors.
The receptor is available in the following formats: stable over-expression cell line,
membrane preparation, or purified receptor in HEK293 or CHO. Various tagged versions
are available.