Human

CSI20174 pdf (datasheet)

1.0 ml

$400.00 BUY

Normal human serum is depleted of Complement C3 by immunoaffinity chromatography. The product is tested for the absence of C3 activity by classical and alternative pathway functional assays and for C3 protein by double immunodiffusion. C3-depleted serum is certified to possess a functional alternative pathway for complement activation after reconstitution with 1.3 mg C3/ml. Similarly, a functional classical pathway can be reconstituted by addition of purified C3 protein (1.3 mg/mL) indicating that all other complement components necessary for classical and alternative pathway activation are present. Although a functional lectin pathway should also be reconstituted by the addition of C3, the function of this pathway is not tested.

> 50 mg protein/ml

CSI20174

Human Serum

Sterile filtered serum diluted with PBS, pH 7.2

No C3 detected by immunodiffusion

Store at -80°C for up to 1 year.