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Human Anti-SARS-CoV-2 Spike-RBD Neutralizing (S2E12) mAb

Synonyms:

Spike glycoprotein, Spike receptor binding domain, Spike-RB protein, S2E12

Species:

SARS-CoV-2

Cat. No.:

CPC541C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

Please Inquire

Concentration:

1.0 mg/ml, lot specific

Description:

New catalog number DVV00318

Recombinant Human anti-SARS-CoV-2 Spike-RBD, Clone S2E12 is expressed in XtenCHO. S2E12 is a fully human anti-SARS-CoV-2 neutralizing monoclonal antibody selected based on binding to RBM across sarbecoviruses related to SARS-CoV-2, potential to neutralize the virus in vitro, including variant Omicron. S2E12 competitively blocks ACE2 attachment.
Available with low endotoxin < 0.01EU/µg, as DVV00318

Entrez Symbol:

S

Uniprot Name:

Spike glycoprotein

Uniprot ID:

P0DTC2

Data PDF:

CPC541

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Specificity:

Recognizes SARS-CoV-2 Spike-RBD, as well as receptor-binding motif (RBM) across sarbecoviruses related to SARS-CoV-2; potential to neutralize the virus in vitro, including variant Omicron. S2E12 competitively blocks ACE2 attachment.

Host Species:

Human

Immunogen:

Derived from a convalescing COVID-19 patient's plasma

Isotype:

IgG1 Kappa light chain

Clone:

S2E12

Formulation:

Sterile-filtered PBS, pH 7.5 preservative free.

Purification:

Protein A affinity chromatography

Application:

ELISA, FS , Neutralizing , WB

Storage/Stability:

Stable at 2-8°C for 1 week or for up to 1 year at -20°C to -80°C. It is recommended to prepare single-use aliquots of undiluted product and store -20°C to -80°C.