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Anti-K48-linked Polyubiquitin (SAA0329) mAb

Synonyms:

Polyubiquitin-C, Ubiquitin, UBC

Species:

Human

Cat. No.:

RHC59302A pdf (datasheet)

Quantity/Size:

100 µg

Price:

$475.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Ubiquitin is a highly conserved protein modifier that heavily accumulates during the oxidative stress response. In the ubiquitin/proteasome system (UPS), the proteasome is the multicatalytic protease, while ubiquitin is the molecular marker that targets protein for degradation. Cellular proteins can be mono-, multi-, or polyubiquitinated, with the latter triggering a multitude of functions depending on which ubiquitin lysine residue is used to link the ubiquitin molecules into a chain. Polyubiquitin chains linked via lysine 48 (K48) are the most abundant and the canonical signal for protein degradation by the proteasome. Anti-K48-linked Polyubiquitin (SAA0329) is a murine monoclonal antibody which targets Human, Mouse, Rat, Rabbit K48-linked Polyubiquitin

Entrez Symbol:

UBC

Uniprot Name:

Polyubiquitin-C

Uniprot ID:

P0CG48

Data PDF:

RHC59302

Purity:

> 95% as determined by SDS-PAGE

Specificity:

Human, Mouse, Rat, Rabbit K48-linked Polyubiquitin

Isotype:

IgG2a kappa light chain

Clone:

SAA0329

Formulation:

0.01M PBS, pH 7.4

Purification:

Protein A/G affinity chromatography from cell culture supernatant

Application:

ELISA, IP , WB

Storage/Stability:

Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.