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Anti-Human MAPT/Tau/PHF-tau (MC1) mAb

Synonyms:

Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau

Species:

Human

Cat. No.:

RHC82420A pdf (datasheet)

Quantity/Size:

100 µg

Price:

$475.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

Tau protein is a microtubule-associated protein, predominantly expressed in the neurons, closely associated with the proper functioning of the cytoskeletal network in terms of microtubule assembly. Tau protein in the CSF is considered as an important biomarker of several disorders of the CNS where axonal damage is contemplated.
In Alzheimer disease, the neuronal cytoskeleton in the brain is progressively disrupted and replaced by tangles of paired helical filaments (PHF) and straight filaments, mainly composed of hyperphosphorylated forms of TAU (PHF-TAU or AD P-TAU).

Entrez Symbol:

MAPT

Uniprot Name:

Microtubule-associated protein tau

Uniprot ID:

P10636

Data PDF:

RHC82420

Purity:

> 95% by SDS-PAGE and SEC-HPLC

Specificity:

Human Microtubule-associated protein tau

Isotype:

IgG2a kappa light chain

Clone:

MC1

Formulation:

100 mM Pro-Ac, 20 mM Arg, pH 5.0 Note: change in formulation

Purification:

Protein A/G affinity chromatography from cell culture supernatant

Application:

ELISA

Storage/Stability:

Recommended storage, undiluted at 2-8°C for up to 1 week, or in working aliquots at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.