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Anti-Human Ganglioside GM1 (F6) mAb

Synonyms:

Ganglioside GM1, Ganglioside A2, Ganglioside G4, Ganglioside GGtet1, Ganglioside GI, Monosialoganglioside GM1

Cat. No.:

RGK28704A pdf (datasheet)

Quantity/Size:

100µg

Price:

$485.00 BUY

Concentration:

1.0 mg/ml, lot specific

Description:

GM1 (monosialotetrahexosylganglioside) the "prototype" ganglioside, is a member of the ganglio series of gangliosides which contain one sialic acid residue. GM1 has important physiological properties and impacts neuronal plasticity and repair mechanisms, and the release of neurotrophins in the brain. Besides its function in the physiology of the brain, GM1 acts as the site of binding for both cholera toxin and E. coli heat-labile enterotoxin. Antibodies to GM1 are increased in Guillain–Barré syndrome, dementia and lupus but their function is not clear.

Data PDF:

RGK28704

Purity:

> 95% by SDS-PAGE.

Specificity:

Human Ganglioside GM1

Host Species:

Human

Isotype:

IgG1 Kappa light chain

Clone:

F6

Formulation:

Sterile-filtered 0.01M PBS, pH 7.4

Purification:

Protein A/G affinity chromatography from cell culture supernatant

Application:

ELISA

Storage/Stability:

Store unopened at -20°C to -80°C for up to 1 year. It is recommended to prepare aliquots and store at -20°C to -80°C. Avoid repeated freeze-thaw cycles.